A common use case for us is to use a formula to highlight data that is missing, out of spec or dates that are missed.

But to then update that data within structure we need to put the associated field next to the formula column and train people to "don't click there on the bold and red item - but go over a few columns to find the same piece of info to update it"

If we had the ability when defining the formula to "Update Field when double clicked: (choose field w/ default of none)" that would allow our use case to be much more intuitive and cleaner.